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Adrian Baez-Ortega

Adrian Baez-Ortega

PhD student


Adrian is an enthusiastic bioinformatician and PhD student at the Transmissible Cancer Group. His strongest academic interest is in understanding the dynamics of the influence exerted by processes of mutagenesis and selection on the cancer genome. His broader interests include molecular evolution, statistical modelling, statistical mechanics and machine learning.

Adrian's current research revolves around the design and application of computational methods for the analysis of high-dimensional genomic data sets, with the aim of unravelling the evolutionary history of CTVT, an 11,000-year-old canine contagious cancer. As part of this research, he has developed Somatypus, a computational pipeline for identifying mutations in large numbers of cancer samples, as well as mutree, a tool for inferring phylogenetic trees and discovering recurrent mutations in them. For this research, Adrian has received the 2017 Abcam Postgraduate Student Prize, awarded by the Department of Veterinary Medicine at Cambridge. Previously, he received an Extraordinary Degree Award and other honours for his computer science studies in Spain, where he developed IonGAP, an online platform for assembly and analysis of bacterial genomes, as well as a workflow for the analysis of metagenomic sequence data.

Adrian's expertise is in somatic variation analysis, statistical programming and computational workflow design. He also writes scientific dissemination articles for his personal website, divulgatum.

See Adrian's profile on LinkedIn | Google Scholar | ORCID | Publons.

Key Publications

Kevin Gori, Adrian Baez-Ortega
bioRxiv (2018)
Preprint DOI: 10.1101/372896
Bernardo Rodriguez-Martin, Eva G. Alvarez*, Adrian Baez-Ortega* et al.
Nature Genetics (in press)
Preprint DOI:
*Authors contributed equally
Sebastian M. Waszak, Grace Tiao, Bin Zhu et al.
(Under review)
Preprint DOI:
Maximilian R. Stammnitz, Tim H. H. Coorens, Kevin C. Gori et al.
Cancer Cell, 33 (4): 607–619 (2018)
DOI: 10.1016/j.ccell.2018.03.013
Adrian Baez-Ortega, Kevin Gori
Briefings in Bioinformatics (2017)
DOI: 10.1093/bib/bbx082
Preprint available on bioRxiv
Fabian Lorenzo-Diaz, Cris Fernández-Lopez, Pierre-Emmanuel Douarre, Adrian Baez-Ortega, Carlos Flores, Philippe Glaser, Manuel Espinosa
Open Biology, 6: 160084 (2016)
DOI: 10.1098/rsob.160084

Adrian Baez-Ortega, Fabian Lorenzo-Diaz, Mariano Hernandez, Carlos Ignacio Gonzalez-Vila, Jose Luis Roda-Garcia, Marcos Colebrook, Carlos Flores
IonGAP: integrative bacterial genome analysis for Ion Torrent sequence data
Bioinformatics, 31(17): 2870–2873 (2015)
DOI: 10.1093/bioinformatics/btv283

Adrian Baez-Ortega
Master’s Thesis, Universidad de La Laguna (2014)

Human anti-cancer drugs could help treat transmissible cancers in Tasmanian devils

« May 2019 »